Our Story
The story of CleopatraRX™ and PearlPAK™ was born out of thoughtful consideration to empower women to take control of their brain health during menopause.
MEET RHONDA R. VOSKUHL, M.D.
Rhonda R. Voskuhl, M.D. has spent her professional career dedicated to finding solutions in neurodegenerative diseases.
A Professor of Neurology at the University of California (UCLA), she considers cognitive issues and the aging population as the greatest challenge of our generation. Dr. Voskuhl is highly regarded by her peers, medical and scientific communities for her research in neuroscience.

Her commitment and tenacity to helping women improve cognition and decrease brain atrophy during menopause, led to the launch of PearlPAK™.
As a result of her extensive research, Dr. Voskuhl found an answer to fill the gap in cognitive deficits in menopausal women.
It was during her research on gray matter atrophy as a key link in multiple sclerosis that Dr. Voskuhl found a definitive connection in the loss of estrogen and its effect on cognitive decline.
It was during her research on gray matter atrophy as a key link in multiple sclerosis that Dr. Voskuhl found a definitive connection in the loss of estrogen and its effect on cognitive decline.
Estrogen plays a proactive role in protecting the hippocampus region of the brain – the area of the brain responsible for active memory, long-term memory, and focus. At the onset of menopause, estrogen sharply declines throughout the body including the estrogen receptors that protect the brain. The loss of estrogen can throw a woman’s body into a frenzy with hot flashes, night sweats, mood swings, weight gain, and brain fog. Brain fog affects verbal memory, attention, and working memory.
PearlPAK™ is the solution. It is not Hormone Replacement Therapy (HRT) which uses estrogen to alleviate common symptoms of menopause but does not address brain health.
The estrogen in PearlPAK™ is estriol, and it binds to different estrogen receptors. By binding to a specific receptor in the brain, estriol offers brain protection. Estriol is considered a safer form of estrogen than other forms of estrogen (estradiol). Estriol has been safely used by menopausal women throughout Europe and Asia for decades.
Timing is important. Neurologists know that one must begin treatment early during mild cognitive impairment to prevent further cognitive deficits. Our goal is to offer treatment at the onset of perimenopause, with the hope of preventing cognitive decline and brain atrophy – before it happens.
We are deeply thankful to inventor Rhonda Voskuhl, M.D. for her long-term commitment and expertise in the research of cognitive health for women and men with multiple sclerosis and for women in menopause.

THE STORY OF CLEOPATRA
The names CleopatraRX and PearlPAK were inspired by the 1st century BCE story of Cleopatra and Mark Antony. Cleopatra, the Pharaoh of Egypt, was highly praised for her intelligence in science, philosophy, math, and debate. Fluent in nine languages, she broke boundaries as a female leader, even learning Egyptian to communicate with her armies.
As the story goes, Cleopatra bet Mark Antony she could host the most expensive dinner ever. During dinner, she dissolved a large pearl in her wine and drank it, making it the costliest meal ever served. Clever. Pearls, known as “The Queen of Gems,” symbolize integrity, balance, serenity, luck, and wisdom, offering protection to those who wear them.
The combination of Cleopatra and the Pearl represents a powerful synergy of strength, making them perfect for our own story.
Together, we are on a mission…
…to empower women to take control of their menopause journey, and to feel confident having conversations with other like-minded and strong women who choose to control their health.
…to empower women to take control of their menopause journey, and to feel confident having conversations with other like-minded and strong women who choose to control their health.