Published Papers

Estrogen receptor beta in astrocytes modulates cognitive function in mid-age female mice

Noriko Itoh, Yuichiro Itoh, Cassandra E. Meyer, Timothy Takazo Suen, Diego Cortez-Delgado, Michelle Rivera Lomeli, Sophia Wendin, Sri Sanjana Somepalli, Lisa C. Golden, Allan MacKenzie-Graham & Rhonda R. Voskuhl
28 September 2023, Nature Communications

 
The X factor in neurodegeneration

Rhonda Voskuhl, Yuichiro Itoh
05 December 2022, Journal of Experimental Medicine

 
Gene expression in oligodendrocytes during remyelination reveals cholesterol homeostasis as a therapeutic target in multiple sclerosis

Rhonda R Voskuhl, Noriko Itoh, Alessia Tassoni, Macy Akiyo Matsukawa, Emily Ren, Vincent Tse, Ellis Jang, Timothy Takazo Suen, Yuichiro Itoh 
14 May 2019, Proceedings of the National Academy of Sciences

Decreased neurofilament light chain levels in estriol-treated multiple sclerosis 

Rhonda Voskuhl, Jens Kuhle, Prabha Siddarth, Noriko Itoh, Kevin Patel, Allan MacKenzie-Graham  
09 August 2022, Annals of Clinical & Translational Neurology

 
Estriol-mediated neuroprotection in multiple sclerosis localized by voxel-based morphometry

Allan MacKenzie-Graham, Jenny Brook, Florian Kurth, Yuichiro Itoh, Cassandra Meyer, Michael J Montag, He-Jing Wang, Robert Elashoff, Rhonda R Voskuhl 
08 September 2018, Brain & Behavior

Estriol combined with glatiramer acetate for women with relapsing-remitting multiple sclerosis: a randomised, placebo-controlled, phase 2 trial

Rhonda R Voskuhl, HeJing Wang, T C Jackson Wu, Nancy L Sicotte, Kunio Nakamura, Florian Kurth, Noriko Itoh, Jenny Bardens, Jacqueline T Bernard, John R Corboy, Anne H Cross, Suhayl Dhib-Jalbut, Corey C Ford, Elliot M Frohman, Barbara Giesser, Dina Jacobs, Lloyd H Kasper, Sharon Lynch, Gareth Parry, Michael K Racke, Anthony T Reder, John Rose, Dean M Wingerchuk, Allan J MacKenzie-Graham, Douglas L Arnold, Chi Hong Tseng, Robert Elashoff
15 January 2016, Lancet Neurology

Oestrogen receptor β ligand acts on CD11c+ cells to mediate protection in experimental autoimmune encephalomyelitis

Roy Y Kim, Darian Mangu, Alexandria S Hoffman, Rojan Kavosh, Eunice Jung, Noriko Itoh, Rhonda Voskuhl,
08 December 2017, Brain

 
Neuroprotection in Cerebral Cortex Induced by the Pregnancy Hormone Estriol

Cassandra E Meyer, Andrew W Smith, Aitana A Padilla-Requerey, Vista Farkhondeh, Noriko Itoh, Yuichiro Itoh, Josephine L Gao, Patrick D Herbig, Quynhanh Nguyen, Katelyn H Ngo, Mandavi R Oberoi, Prabha Siddarth, Rhonda R Voskuhl, Allan MacKenzie-Graham
August 2023, Laboratory Investigation

 
Estriol preserves synaptic transmission in the hippocampus during autoimmune demyelinating disease

Marina O Ziehn, Andrea A Avedisian, Shannon M Dervin, Thomas J O’Dell and Rhonda R Voskuhl
August 2012, Laboratory Investigation

Estrogen Treatment Prevents Gray Matter Atrophy in Experimental Autoimmune Encephalomyelitis

Allan J. MacKenzie-Graham, Gilda A. Rinek, Andrea Avedisian, Laurie B. Morales, Elizabeth Umeda, Benoit Boulat, Russell E. Jacobs, Arthur W. Toga, and Rhonda R. Voskuhl
July 2012, Journal of Neuroscience

Treatment of multiple sclerosis with the pregnancy hormone estriol

Nancy L Sicotte, Stephanie M Liva, Rochelle Klutch, Paul Pfeiffer, Seth Bouvier, Sylvia Odesa, T C Jackson Wu, Rhonda R Voskuhl
October 2002, Annals of Neurology